Nicotinamide Riboside Supplementation Improves Fetal Growth Under Hypoglycemia: Preclinical Findings

Synopsis Nicotinamide riboside (NR), a form of vitamin B3 known for its metabolic benefits, may play an important role in glucose control during pregnancy. This study examined how NR affects blood...

Beyond Pellagra—NAD+ Deficiency in Aging and Disease: Review

SynopsisInterest in NAD+ has surged because low NAD+ levels are linked to many health problems, including metabolic diseases, neurodegeneration, reproductive disorders, cancer, and aging. Researche...

Nicotinamide Riboside Supplementation Improves Post-Ovulatory Oocyte Quality: Preclinical Findings

Synopsis As eggs age after ovulation, their quality declines, reducing the chances of successful fertilization and embryo development during assisted reproductive technology (ART) procedures like ...

Nicotinamide Riboside Prevents Low Kidney Nephron Numbers Caused by Maternal Protein Restriction: Preclinical Findings

SynopsisBabies born with fewer nephrons (kidney filters), often due to poor maternal nutrition, have higher risk for kidney disease and high blood pressure later. There are no current treatments to...

Nicotinamide Riboside May Help Reactivate Early Human Embryos in IVF: Preclinical Findings

Synopsis During in vitro fertilization (IVF), nearly 60% of human embryos stop developing early—between the 3- and 8-cell stages—making it a major challenge for successful pregnancies. This study ...

Nicotinamide Riboside Restores NAD+ and Mitochondrial Health in Polycystic Ovary Syndrome: Preclinical Findings

Synopsis Polycystic ovary syndrome (PCOS) is a common hormonal disorder that causes ovulation problems, infertility, and insulin resistance. Researchers found that women with PCOS have lower level...

Nicotinamide Riboside Improves Ovarian Health and Fertility in Aging: Preclinical Findings

Synopsis As female mice age, their ovaries lose follicles and the quality of eggs declines, partly due to lower levels of NAD+. In this study, supplementing aging mice with nicotinamide riboside (...

Nicotinamide Riboside Enhances Blood Stem Cell Recovery and Regeneration: Preclinical Findings

Synopsis Recent studies show that increased mitochondrial activity and impaired stress response harm hematopoietic stem cells (HSCs), reducing their ability to regenerate. This study found that NR...