Nicotinamide Riboside Restores NAD+ and Improves Mitochondrial Function in HIV-Nephropathy: Preclinical Findings

SynopsisHIV disease remains prevalent in the United States and especially in sub-Saharan Africa. In mice with HIV-associated kidney disease (HIVAN), their kidney cells showed mitochondrial dysfunct...

Nicotinamide Riboside Protects Kidneys after Heart Attack: Preclinical Findings

SynopsisCardiorenal syndrome type 1 occurs when acute kidney injury (AKI) develops after sudden heart problems like a heart attack (MI), increasing the risk of death. This study tested whether nico...

Nicotinamide Riboside Protects Against Diabetic Kidney Disease: Preclinical Findings

SynopsisDiabetic kidney disease (DKD) is a leading cause of kidney failure, linked to inflammation and mitochondrial dysfunction. This study evaluated whether boosting NAD+ metabolism via nicotinam...

Nicotinamide Riboside Protects Against Chronic Kidney Disease by Boosting Metabolism: Preclinical Findings

SynopsisChronic kidney disease (CKD) impairs kidney metabolism, including fatty acid breakdown, and is linked to low NAD+ levels. This study tested nicotinamide riboside (NR), a precursor of NAD+, ...

Nicotinamide Riboside Prevents Low Kidney Nephron Numbers Caused by Maternal Protein Restriction: Preclinical Findings

SynopsisBabies born with fewer nephrons (kidney filters), often due to poor maternal nutrition, have higher risk for kidney disease and high blood pressure later. There are no current treatments to...

Nicotinamide Riboside and CoQ10 Supplementation May Support Kidney Health in Chronic Kidney Disease: Clinical Findings

Objectives To examine the effects of NR and coenzyme Q10 (CoQ10) supplementation alone for six weeks on physical endurance, work efficiency, and metabolic profile in chronic kidney disease (CKD) p...