What Is Mitochondrial Health? Energy, NAD+, and the Science of Aging

Mitochondrial decline is now recognized as a hallmark of aging and a driving mechanism behind many age-related conditions. Learn more about mitochondrial health, the role of NAD+ in supporting it, ...

The Role of NAD+ in Muscle Health, Aging, and Physical Performance

NAD+ is essential to nearly every process that keeps muscles functioning–from powering contractions to repairing damage after exercise. But levels decline significantly with age, and the impact on ...

Does NAD+ Decline with Age? Yes, But Blood NAD+ and Tissue NAD+ Are Not the Same

A newly published study reports that whole blood NAD+ does not decline with age, failing to account for well-documented tissue-specific declines. Human data from brain, muscle, skin, and liver cont...

NAD+ and Brain Health: What the Science Actually Says About Aging, Neurodegeneration, and Cognitive Function

NAD+ is one of the most important molecules in your brain, and it declines with age. From Alzheimer's and Parkinson's to mild cognitive impairment, scientists are uncovering how that decline may dr...

Inside the NAD for Health Conference in Copenhagen: Key Takeaways from the World's Leading NAD+ Researchers

The NAD for Health conference, top researchers spent three days doing what the NAD+ field needed: having a robust, unfiltered conversation about the science. Here is what they found–promising early...

Nicotinamide Riboside Injections: What Two New Pilot Studies Reveal About Safety

Two first-of-their-kind pilot studies have evaluated the safety of subcutaneous and intramuscular NR injections in humans, and the short-term findings are cautiously encouraging. Learn what the cli...

Can Increasing NAD+ Support Reproductive Health and Fertility?

Emerging research suggests that NAD+, a key molecule for cellular energy and DNA repair, may support reproductive health—from egg and sperm quality to pregnancy outcomes and offspring development. ...

The 14 Hallmarks of Aging: How NAD+ Plays a Role in Every Hallmark

Key Takeaways Aging is a system of biological processes, not isolated events: 14 biological and psychological/social hallmarks interact to drive the aging process. NAD+ is a central hub: A decl...

NR vs. NMN: What the Latest Human Research Actually Shows

Two newly published clinical studies tested NR and NMN head-to-head in humans for the first time. Explore what the latest clinical data reveals about which NAD+ precursor is more effective at incre...

Nicotinamide Riboside Chloride Now Has a USP Monograph—Here’s What That Means

The United States Pharmacopeia (USP) has published a compendial standard for nicotinamide riboside chloride (NRCl), making it one of the only NAD+ precursors to meet pharmacopeial quality benchmark...

What Is a Patent? Types, Uses, and Why They Matter for NAD+

Patents are the foundation of innovation, but understanding what they are and how they work is more nuanced than it may seem. This educational guide breaks down the types of patents, what each prot...

NAD+ IV Therapy vs. NR IV Therapy: What Clinical Research Reveals About Safety, Efficacy, and Why It Matters

NAD+ cannot enter cells directly, and that biological reality has major implications for NAD+ IV therapy. Two clinical studies comparing NR IV and NAD+ IV head-to-head reveal what that means in pra...

Peripheral Artery Disease and NAD+: Mitochondrial Health, Vascular Aging, and Emerging Clinical Evidence

Peripheral artery disease impacts over 200 million people globally, causing pain, reduced mobility, and increased cardiovascular risk. Emerging evidence links NAD+ to improved mitochondrial and vas...

The Role of NAD+ in Immune Health and Function

Explore how NAD+, an essential cellular molecule, supports immune health through its roles in energy production, DNA repair, and inflammation regulation. Learn how viral infections and immune stres...

NAD+ and Cancer: Current Research on Supplementation Safety and Risk

As NAD+ supplementation grows in popularity, questions about cancer risk have emerged. This article breaks down the research, highlights misleading media claims, and delves into the nuanced science...

Can NAD+ Help with Long COVID Recovery? What We Know

New research suggests that nicotinamide riboside (NR), a precursor to NAD+, may help improve long COVID symptoms like fatigue, mood, and sleep quality. Explore the science behind this potential mol...

FDA Classifies NAD+ Injection Recalls: Understanding the Safety Risks and What You Need to Know About Endotoxins and Quality

The U.S FDA has classified two recalls of NAD+ injections from GenoGenix, LLC, with the latest Class I recall linked to dangerous endotoxin contamination. Find out which products are affected, the ...

Can Increasing NAD+ Support Skin Health & Aging?

Explore how NAD+ supports skin health, why its levels decline with age, and how nicotinamide riboside (NR) may help boost NAD+ from the inside out to support healthy skin.

No Evidence Shows That Oral NAD+ Supplementation Increases NAD+ Levels in Humans

Oral NAD+ supplements have not been shown to increase NAD+ levels in humans, a conclusion recently supported by the National Advertising Division (NAD). Learn why the science shows oral NAD+ is ine...

FDA Reverses NMN Decision: Risks, Quality Concerns, and Alternative Options

The U.S. FDA reversed its previous ban on NMN supplements, yet low-quality products and patent challenges pose risks. Explore safe, more effective NAD+ precursors backed by science.