Re-Balancing NAD+ Metabolism Blunts the Impact of Telomere Dysfunction in Human Cells, Mice

A recent study published in The European Molecular Biology Organization Journal, conducted by investigators at the National Institute on Aging (NIA) and the National Cancer Institute (NCI), both di...

New Phase 2 Clinical in COVID-19 Patients Finds Hydroxychloroquine (HCQ) Plus Nutritional Protocol Including Nicotinamide Riboside Significantly Improved Recovery Time Vs. HCQ Alone

On the heels of two previously published preclinical studies investigating the effect of viral infection on NAD+ levels, new clinical research in 93 mild-to-moderate COVID-19 infected patients is n...

Elderly Patients with Heart Failure Have Lower NAD+ Levels

A new study published in Experimental Gerontology found that among 170 blood donors, elderly patients with heart failure had the lowest NAD+ levels, which suggests a role for NAD+ precursors in sup...

First-of-its-kind Agricultural Study Finds In Ovo Feeding of Nicotinamide Riboside Affects Poultry Broiler Pectoralis Major Muscle Development

A study published in Translational Animal Science finds that in ovo nicotinamide riboside (NR) injections increased chick pectoralis major (PM) muscle weight, length, width, and depth – a result wh...

All Eyes on NAD+ as Preclinical Study Demonstrates Protection Against Light-Induced Retinal Degeneration

A recent study found that raising NAD+ levels in a mouse model could protect the survival and function of retinal cells, the cells responsible for sight, against damaging UV light.

NAD+ May Modulate Inflammation in End-Stage Heart Failure Patients

Raising NAD+ levels with the precursor Nicotinamide Riboside (NR) was found to reduce markers of inflammation in the blood from a small group of Stage D heart failure (HF) patients.

Nicotinamide Riboside May Offer Unique Protection Against Endothelial Inflammation

A new study shows that while both nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) can help protect against blood-vessel inflammation by raising NAD+, NR may be the more direct and ...

Raising NAD+ With Nicotinamide Riboside Resolved Social Deficits in Autism Mouse Model

An autism model developed in male mice supplemented with nicotinamide riboside (NR) was found to have restored levels of the neurotransmitter oxytocin and improved social behavior.

Raising NAD+ Levels May Support Mitochondrial Health and Fertility in Aging

Recent studies have shown that increasing cellular nicotinamide adenine dinucleotide (NAD+) levels can restore metrics of fertility, such as oocyte (immature egg) count and health, among aging mice.

Raising NAD+ Levels With Niagen® (Nicotinamide Riboside) Inhibits Coronavirus Replication in Preclinical Cell Model

New preclinical research shared on scientific publishing website bioRxiv.org has demonstrated that increasing NAD+ levels can boost the activity of protective enzymes called PARPs and reduce corona...

Innate Immunity: The Body’s Security Force

Innate immunity is the body’s first line of defense against infection which is why this powerful security system needs all the fuel it can get. One cellular energy carrier critical to this process ...

Nicotinamide Riboside Restores A More "Youthful" Circadian Rhythm In Mice

A new preclinical study published in Molecular Cell, out of Northwestern University, found that boosting NAD+ levels with nicotinamide riboside (NR) could turn back the clock on cellular aging in m...

NAD+ Liver Depletion is Linked to Alcohol-Related Liver Disease in Humans

A new study recently published in Hepatology Communications  and conducted by investigators from The University of Birmingham, its affiliated hospital, and the University of Iowa, found that NAD+ l...

Inflammation: A Double Edge Sword in Immunity

The latest research suggests NAD+ may play a central role in regulating inflammation for an effective—but targeted—immune response to dangerous pathogens such as the Coronavirus.

Increasing Nicotinamide Adenine Dinucleotide (NAD+) with Nicotinamide Riboside (NR) Reduced Neurodegeneration, and Increased Lifespan in Preclinical Model

The human body is composed of cells in the trillions. Each cell relies on a resource molecule called NAD+ for the generation of energy we know as ATP. This energy helps cells perform their unique f...

What is the Link Between NAD+ and Your Cells’ Innate Immune Response?

Just like our planet is mustering up the resources to fight the ongoing COVID-19 (Coronavirus) pandemic, so too do our cells need energy to support cellular repair. NAD+ may hold the key to support...

New Study Deepens Link Between Heart Failure and Mitochondrial Health

The heart is a hard-working muscle. Each day it beats approximately 100,000 times without any breaks. It’s been estimated that over the course of an average lifetime, the human heart will beat more...

First Study To Measure Postpartum NAD Levels Is Out Now

New moms don’t need scientists to tell them that postpartum is stressful. As if bringing a new life into the world isn’t hard enough, moms have to adjust to an ever-changing body and new identity w...

What the Science Says About B3 Vitamins and Methylation

You spend enough time reading up on B3 vitamins, you’ll inevitably come across a bunch of terms that start with methyl: methyl group, methyl donor, methylation. But before you get caught up in the ...

NR Shows Potential to Reduce Fatty Liver in People

A clinical study conducted at the University of Copenhagen, Aarhus University Hospital and the University of Iowa has provided the first human evidence of the potential for nicotinamide riboside (N...