Nicotinamide Riboside Supports Cartilage Cell Survival and Normal Bone Growth: Preclinical Findings

Synopsis Nicotinamide adenine dinucleotide (NAD+) is critical for energy metabolism and bone development. Researchers generated mice lacking NAMPT, an essential enzyme in the NAD+ salvage pathway,...

Nicotinamide Riboside Restores NAD+ and Prevents Age-Related Bone Loss: Preclinical Findings

SynopsisAge-related osteoporosis happens because of a decline in osteoblasts—the cells that build bone—and fewer osteoblast progenitor cells, which show signs of aging called senescence. FoxO trans...