NAMPT Deficiency in Mouse Liver Cells Shows Minimal Impact on NAD+ and Mitochondrial Health: Preclinical Findings

Synopsis Supplementation with NAD+ precursors such as nicotinamide riboside (NR) has been shown to improve mitochondrial function and prevent liver fat accumulation in high-fat diet (HFD)-fed rode...

Nicotinamide Riboside Demonstrates Cardioprotective Effects by Boosting Mitochondrial Stress Response: Preclinical Findings

Synopsis The mitochondrial unfolded protein response (UPRmt) helps cells manage misfolded proteins in mitochondria to maintain function. Cardiac mitochondria are essential for contractile function...

Nicotinamide Riboside Supplementation Benefits in Werner's Syndrome: Clinical Findings

Objectives To evaluate the safety and efficacy of oral NR supplementation in patients with Werner Syndrome (WS). Journal Aging Cell Key Outcomes NR improved arterial stiffness, as measured by the...