Variable Selection in Untargeted Metabolomics and the Danger of Sparsity
Objective
To study the metabolic effects of treatment with NR in a cohort of patients with ataxia-telangiectasia (AT).
Study Design
Comparative study in 14 patients with AT
Dose
25 mg/kg
Duration
4 months
Key Outcomes
NR-related pathways and metabolites significantly increased after NR supplementation.