Nicotinamide Riboside Protected Muscle Cells from Heat-Induced Injury: Preclinical Findings

Synopsis Prolonged exposure to heat stress can damage skeletal muscle (SKM) by disrupting mitochondrial function, but the mechanisms behind this injury are not fully understood. This study found t...

Nicotinamide Riboside Partially Restores Cellular Energy in Mitochondrial Disease: Preclinical Findings

Synopsis Mitochondrial diseases arise from genetic mutations that impair energy production in cells. One of the most common, the m.3243A>G mutation, disrupts complex I of the mitochondrial resp...

Effects of Nicotinamide Riboside on Mitochondrial Function in Rare Mitochondrial Disorder: Preclinical Findings

Synopsis Nicotinamide riboside (NR), a vitamin B3 derivative and precursor to NAD+, is known to support mitochondrial function and energy metabolism in many conditions. Researchers tested whether ...

Nicotinamide Riboside Improves Mitochondrial Function in Mutant Human Cells: Preclinical Findings

Synopsis Mitochondrial disorders are severe genetic conditions that disrupt energy production, and currently, no effective treatments exist. This study explored whether boosting NAD+, a vital mole...

Nicotinamide Riboside Improved Endurance in Mitochondrial Disease: Preclinical Findings

Synopsis Mitochondrial disorders are rare but serious diseases caused by defects in the cell’s energy-producing machinery, known as the mitochondrial respiratory chain. These conditions often lead...