Article: Nicotinamide Riboside Supplementation Enhances NAD+ Metabolism in Ataxia Telangiectasia: Clinical Findings

Nov 17, 2020 Ataxia Telangiectasia Clinical Neurological Health

Nicotinamide Riboside Supplementation Enhances NAD+ Metabolism in Ataxia Telangiectasia: Clinical Findings

Objectives

To study the metabolic effects of treatment with NR in a cohort of patients with ataxia-telangiectasia (AT).

Journal

Metabolites

Key Outcomes

NR-related pathways and metabolites significantly increased after NR supplementation.

Duration

4 months

Dose

25 mg/kg

Study Design

Comparative study in 14 patients with ataxia telangiectasia (AT)

See Published Study

Amyotrophic Lateral Sclerosis (ALS)

Nicotinamide Riboside and Pterostilbene Protect Motor Neurons in ALS: Preclinical Findings

Synopsis Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the gradual loss of motor neurons, largely due to oxidative stress and inflammation. In both human trials an...

Cellular Health

Nicotinamide Riboside Protects Lens Cells from Oxidative Stress: Preclinical Findings

Synopsis Researchers found that nicotinamide riboside (NR), a vitamin B3 derivative and NAD+ precursor, can protect eye lens cells from oxidative stress, one of the main causes of cataracts. In la...