Nicotinamide Riboside Reduces Airway Inflammation in COPD: Clinical Findings

Objectives To investigate the effects of NR supplementation on airway inflammation and cellular senescence in previously smoking patients with chronic obstructive pulmonary disease (COPD). Journal...

Nicotinamide Riboside Reverses Pulmonary Hypertension: Preclinical Findings

Synopsis Pulmonary hypertension (PH) is a deadly lung vascular disease caused by endothelial dysfunction and vascular remodeling that strain the heart. This study identified Sirtuin 7 (SIRT7)—a NA...

Effects of Nicotinamide Riboside on Bacterial Respiratory Epithelial Infections: Preclinical Findings

Synopsis This study found that during infection, lung cells experience a breakdown in the NAD+ salvage pathway, which reduces NAD+ production—a molecule crucial for energy metabolism and immune de...

Nicotinamide Riboside Protects Against Paraquat-Induced Lung Injury: Preclinical Findings

Synopsis Paraquat, a highly toxic herbicide, can cause severe oxidative lung damage and high mortality. This study investigated whether nicotinamide riboside (NR), a vitamin B3 derivative, can pro...

Nicotinamide Riboside and NMN Enhance Regeneration of Lung Cells in 3D Culture: Preclinical Findings

Synopsis Type 2 alveolar epithelial cells (AEC2s) are crucial for repairing and regenerating lung tissue after injury. This study found that in both idiopathic pulmonary fibrosis (IPF) patients an...