Effects of Nicotinamide Riboside in Duchenne Muscular Dystrophy: Preclinical Findings

Synopsis Duchenne muscular dystrophy (DMD) causes progressive muscle wasting due to loss of dystrophin. In dystrophin-deficient mice, muscles show depletion of NAD, an important metabolic cofactor...

Nicotinamide Riboside Improves Muscle Function in Duchenne Muscular Dystrophy: Preclinical Findings

Synopsis Neuromuscular diseases such as Duchenne muscular dystrophy (DMD) arise from genetic mutations that cause progressive muscle weakness and degeneration. This study identifies nicotinamide a...

Nicotinamide Riboside Rejuvenates Aged Muscle Stem Cell Function: Preclinical Findings

Synopsis Aging reduces the regenerative capacity of tissues by driving senescence in adult stem cells (SCs), including those that repair muscle, brain, and skin. This study identifies declining le...