Article: Standardized Assay Quantifies NAD+ and NADH in Worms, Mice, and Human Blood: Preclinical Findings

Nov 1, 2024 Cellular Health Preclinical

Standardized Assay Quantifies NAD+ and NADH in Worms, Mice, and Human Blood: Preclinical Findings

Synopsis

A standardized assay was developed to measure NAD+, NADH, and the NAD+/NADH ratio across multiple biological samples, including C. elegans, mouse muscle, mouse blood, and human blood. The protocol provides clear steps for sample collection, preparation, and measurement, making it broadly applicable for quantifying NAD+ and NADH in different models.

Journal

STAR Protocols

See Published Study

Neurological Health

Nicotinamide Riboside Protects Dopamine Neurons in Parkinson's Disease: Preclinical Findings

Synopsis This study identified the essential role of NAMPT, an enzyme that helps produce NAD+, in protecting dopaminergic neurons—the brain cells that control movement and are lost in Parkinson’s ...