Article: Standardized Assay Quantifies NAD+ and NADH in Worms, Mice, and Human Blood: Preclinical Findings

Cellular Health Preclinical

Standardized Assay Quantifies NAD+ and NADH in Worms, Mice, and Human Blood: Preclinical Findings

Synopsis

A standardized assay was developed to measure NAD+, NADH, and the NAD+/NADH ratio across multiple biological samples, including C. elegans, mouse muscle, mouse blood, and human blood. The protocol provides clear steps for sample collection, preparation, and measurement, making it broadly applicable for quantifying NAD+ and NADH in different models.

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STAR Protocols

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Glaucoma

SARM1 Drives Nerve Damage Following Inflammation and Cell Death Signals: Preclinical Findings

SynopsisNeuroinflammation and a type of cell death called necroptosis play big roles in neurodegenerative diseases, often starting with damage to nerve fibers called axons. SARM1 is a key enzyme th...

Glaucoma

SARM1 Drives Nerve Damage Following Inflammation and Cell Death Signals: Preclinical Findings

Standardized Assay Quantifies NAD+ and NADH in Worms, Mice, and Human Blood: Preclinical Findings

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