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Article: Nicotinamide Riboside—Therapeutic Applications and Current State of Research: Review

Nicotinamide Riboside—Therapeutic Applications and Current State of Research: Review


Synopsis

Nicotinamide riboside (NR) is a form of vitamin B3 and a building block for NAD+, a coenzyme essential for energy production, DNA repair, and cell communication. NR has gained attention for its potential benefits in brain health, mitochondrial function, and healthy aging, and is available as a dietary supplement under study for medical uses. NR can be made in crystalline or amorphous forms—crystalline is more stable and easier to produce consistently, while amorphous may dissolve better and be absorbed more easily, though it's less stable. Supplement makers choose the form based on factors like stability, solubility, and product type.

JOURNAL

Matrix Science Pharma

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Nicotinamide Riboside Supplementation and Exercise Are Safe and Feasible in Childhood Cancer Survivors: Clinical Findings

Objectives To evaluate the feasibility and efficacy of a remote telehealth exercise program, with or without NR supplementation, on improving glucose homeostasis and muscle health in adult childho...

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Nicotinamide Riboside Supplementation with Metabolic Activators Improves Cognitive Function in Parkinson’s Disease: Clinical Findings

Objectives To investigate whether supplementation of combined metabolic activators (CMA) consisting of NR, L-carnitine tartrate, serine, and N-acetyl-L-cysteine (NAC), could be used to treat Parki...

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