Skip to content

Article: Nicotinamide Riboside—Therapeutic Applications and Current State of Research: Review

Nicotinamide Riboside—Therapeutic Applications and Current State of Research: Review


Synopsis

Nicotinamide riboside (NR) is a form of vitamin B3 and a building block for NAD+, a coenzyme essential for energy production, DNA repair, and cell communication. NR has gained attention for its potential benefits in brain health, mitochondrial function, and healthy aging, and is available as a dietary supplement under study for medical uses. NR can be made in crystalline or amorphous forms—crystalline is more stable and easier to produce consistently, while amorphous may dissolve better and be absorbed more easily, though it's less stable. Supplement makers choose the form based on factors like stability, solubility, and product type.

JOURNAL

Matrix Science Pharma

Read more

Cardiovascular Disease

NAD+ Metabolism and Heart Failure: Review

SynopsisNAD+, along with its reduced form NADH, is central to energy metabolism and is also the starting point for NADP+ production and a co-substrate for key enzymes that regulate oxidative stress...

Read more
Amyotrophic Lateral Sclerosis (ALS)

NAD+ Augmentation as a Disease-Modifying Strategy for Neurodegeneration: Review

SynopsisNeurodegenerative diseases are a growing global health problem with no current treatments that slow or stop their progression. Boosting nicotinamide adenine dinucleotide (NAD+) has emerged ...

Read more