Article: Nicotinamide Riboside Supplementation Modestly Improves Body Composition & Sleeping Metabolic Rate: Clinical Findings

Apr 22, 2020 Clinical Metabolic Health Muscle Health

Nicotinamide Riboside Supplementation Modestly Improves Body Composition & Sleeping Metabolic Rate: Clinical Findings

Objectives

To investigate the effects of NR supplementation on insulin sensitivity, mitochondrial function, and other metabolic health parameters in overweight and obese volunteers.

Journal

The American Journal of Clinical Nutrition

Key Outcomes

NR supplementation significantly increased markers of enhanced NAD+ metabolism in human skeletal muscle (e.g., NAAD and MeNam).
Minor beneficial changes in body composition, sleeping metabolic rate, and skeletal muscle acetyl-carnitine concentrations were found.

Duration

6 weeks

Dose

1000 mg

Study Design

Randomized, double-blind, placebo-controlled crossover study in 15 healthy, overweight or obese, sedentary men and women

See Published Study

Clinical

The Effects of NAD+ Boosting on Muscle Mitochondrial Function: Clinical Findings

Objectives To determine if NR supplementation in middle-aged, obese, insulin-resistant men affects mitochondrial respiration, content and morphology in skeletal muscle. Journal The Journal of Phys...