Article: Nicotinamide Riboside Supplementation Modestly Improves Body Composition & Sleeping Metabolic Rate: Clinical Findings

Clinical Metabolic Health Muscle Health

Nicotinamide Riboside Supplementation Modestly Improves Body Composition & Sleeping Metabolic Rate: Clinical Findings

Objectives

To investigate the effects of NR supplementation on insulin sensitivity, mitochondrial function, and other metabolic health parameters in overweight and obese volunteers.

Journal

The American Journal of Clinical Nutrition

Key Outcomes

NR supplementation significantly increased markers of enhanced NAD+ metabolism in human skeletal muscle (e.g., NAAD and MeNam).
Minor beneficial changes in body composition, sleeping metabolic rate, and skeletal muscle acetyl-carnitine concentrations were found.

Duration

6 weeks

Dose

1000 mg

Study Design

Randomized, double-blind, placebo-controlled crossover study in 15 healthy, overweight or obese, sedentary men and women

See Published Study

Metabolic Health

Nicotinamide Riboside Enhances Muscle Growth and Fiber Density in Chicken Embryos: Preclinical Findings

Synopsis Researchers injected nicotinamide riboside (NR) into fertilized chicken eggs to study its effects on muscle growth. NR increased the weight, length, and width of the pectoral muscles in c...

Clinical

Nicotinamide Riboside Supplementation Combined with Metabolic Cofactors Shows Promise for NAFLD: Clinical Findings

Objectives To assess the tolerability and metabolic effects of combined supplementation with combined metabolic activators (CMA), L-serine, NAC, nicotinamide riboside, and L-carnitine in healthy h...