Article: Nicotinamide Riboside Helps Prevent Obesity, Inflammation, and Fibrosis: Preclinical Findings

May 25, 2022 Inflammation Metabolic Health Obesity Preclinical

Nicotinamide Riboside Helps Prevent Obesity, Inflammation, and Fibrosis: Preclinical Findings

Synopsis

NR supplementation was tested in young and old obese female mice to see if it reduces liver inflammation and fibrosis. In old mice, NR decreased weight gain, fat mass, and improved glucose tolerance and cholesterol levels. Although it did not reduce liver fat or fibrosis, NR significantly reduced inflammation and fibrosis in fat tissue and increased metabolism and activity. NR had little effect in young mice. These results indicate NR may help prevent obesity-related fat tissue damage in older females.

Journal

The Journal of Nutritional Biochemistry

See Published Study

Neurological Health

Nicotinamide Riboside Prevents Nerve Damage From Toxic Chemicals: Preclinical Findings

Synopsis Organophosphate-induced delayed neuropathy (OPIDN) is a serious condition caused by exposure to certain toxic chemicals, leading to nerve degeneration similar to Wallerian degeneration, w...

Autism Spectrum Disorder

Autism-Linked Gene NRXN1 Found to Affect Mitochondrial Energy and Metabolism: Preclinical Findings

Synopsis Autism is often linked to differences in language, social interaction, and repetitive behaviors, but it is increasingly recognized that energy metabolism and mitochondrial dysfunction can...

Nicotinamide Riboside Helps Prevent Obesity, Inflammation, and Fibrosis: Preclinical Findings

Synopsis

Journal

Read more