Skip to content

Article: Nicotinamide Riboside Supplementation May Influence Bacterial Composition: Clinical Findings

Nicotinamide Riboside Supplementation May Influence Bacterial Composition: Clinical Findings


Objectives

To explore the effects of NR supplementation on the gut microbiota composition in humans.

Journal

npj Aging

Key Outcomes

  • NR supplementation did not affect the diversity or abundance of gut bacteria in humans. However, NR increased (albeit not significantly) the ratio of Firmicutes and Proteobacteria, suggesting a potential positive effect.

Duration

12 weeks

Dose

2000 mg

Study Design

Randomized, double-blind, placebo-controlled, parallel assignment study in 40 healthy, obese sedentary men

Read more

Cellular Health

Metabolic Engineering of E. coli Enables Efficient Biosynthesis of Nicotinamide Riboside: Preclinical Findings

Synopsis Researchers developed a highly efficient biotechnological method to produce nicotinamide riboside (NR)—a vital precursor of NAD+—using engineered E. coli bacteria. They identified that th...

Read more
Cardiovascular Health

Interferon-β in Combination with Nicotinamide Riboside Offers Protection Against Sepsis: Preclinical Findings

Synopsis Sepsis is a severe, often fatal condition in which the body’s immune response to infection causes widespread inflammation and organ failure. This study found that combining interferon-β (...

Read more