Article: Nicotinamide Riboside Supplementation May Influence Bacterial Composition: Clinical Findings

Clinical Digestive/Gut Health

Nicotinamide Riboside Supplementation May Influence Bacterial Composition: Clinical Findings

Objectives

To explore the effects of NR supplementation on the gut microbiota composition in humans.

Journal

npj Aging

Key Outcomes

NR supplementation did not affect the diversity or abundance of gut bacteria in humans. However, NR increased (albeit not significantly) the ratio of Firmicutes and Proteobacteria, suggesting a potential positive effect.

Duration

12 weeks

Dose

2000 mg

Study Design

Randomized, double-blind, placebo-controlled, parallel assignment study in 40 healthy, obese sedentary men

See Published Study

Clinical

Nicotinamide Riboside Supplementation Does Not Disrupt Methylation, Including in Individuals with MTHFR Mutations: Clinical Findings

Objectives To investigate the impact of NR supplementation on DNA methylation patterns in the blood cells and muscle tissues of newly diagnosed, dopaminergic treatment-naïve Parkinson's disease (P...