Article: Nicotinamide Riboside and Pterostilbene Do Not Improve Muscle Recovery: Clinical Findings

Aug 23, 2022 Clinical Muscle Health

Nicotinamide Riboside and Pterostilbene Do Not Improve Muscle Recovery: Clinical Findings

Objectives

To determine whether nicotinamide riboside and pterostilbene (NRPT) supplementation helps activate muscle stem cells and supports muscle repair after a small, controlled injury in elderly adults.

Journal

JCI Insight

Key Outcomes

NRPT supplementation increased blood NAD+ levels, but did not improve muscle stem cell recruitment, size, or proliferation after muscle injury.

Duration

6 weeks

Dose

1000 mg NR + 200 mg PT

Study Design

Randomized, double-blind, placebo-controlled clinical study in 32 elderly subjects

See Published Study

Metabolic Health

Nicotinamide Riboside Shifts Human Fat Cells Toward Energy-Burning Beige Cells: Preclinical Findings

SynopsisBeige fat cells play key roles in organismal energy and metabolic balance. NR supplementation of human white fat cells derived from stem cells induced mitochondrial biogenesis and expressio...