Nicotinamide Riboside Supplementation and Exercise Are Safe and Feasible in Childhood Cancer Survivors: Clinical Findings
Objectives
To evaluate the feasibility and efficacy of a remote telehealth exercise program, with or without NR supplementation, on improving glucose homeostasis and muscle health in adult childhood cancer survivors with prediabetes.
Journal
Pediatric Blood & Cancer
Key Outcomes
- As a feasibility study, the target of achieving ≥70% compliance with both the exercise and NR interventions was successfully met, indicating that this approach was well-received by the patient population.
- NR supplementation showed no significant effects on markers of glucose metabolism, body composition, or muscle strength.
Duration
6 weeks
Dose
1000 mg
Study Design
Randomized, double-blind, placebo-controlled, pilot study in 20 childhood cancer survivors with prediabetes