Article: Early Nicotinamide Riboside Supplementation Shows Promise in an Individual with Ataxia Telangiectasia: Case Report

Oct 12, 2022 Ataxia Telangiectasia Case Studies Neurological Health

Early Nicotinamide Riboside Supplementation Shows Promise in an Individual with Ataxia Telangiectasia: Case Report

Objective

To investigate the effects of NR supplementation in a 3.5-year-old male child with ataxia and recurrent bacterial infections. This was a case study of one individual.

Journal

Neuropediatrics

Key Outcomes

NR supplementation resulted in no adverse effects.
Neurological examination after 7 and 11 months of NR supplementation showed a clearer and more fluid speech and improvement in fine motor skills and movement disorder.
Use of antibiotics and frequency of hospitalizations due to infections were reduced by more than 90%.
The authors stated given the absence of adverse effects, they strongly encourage to consider NR supplementation in all individuals with ataxia telangiectasia.

Duration

11 Months

Dose

25 mg/kg

Study Design

Clinical case study in 1 3.5-year-old child of Syrian parents

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