Article: Nicotinamide Riboside Supplementation Increases Brain NAD+ Levels in Humans: Clinical Findings

Jul 23, 2024 Clinical Neurological Health

Nicotinamide Riboside Supplementation Increases Brain NAD+ Levels in Humans: Clinical Findings

Objectives

To investigate the effects of acute NR supplementation on cerebral NAD+ levels in the healthy human brain using a specialized MRI technique called downfield proton magnetic resonance spectroscopy (DF1H MRS).

Journal

Magnetic Resonance in Medicine

Key Outcomes

NR supplementation significantly increased brain NAD+ levels by about 16% compared to baseline...

Duration

4 hours

Dose

900 mg

Study Design

Open-label, pilot study in 10 healthy subjects

See Published Study

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