Article: Nicotinamide Riboside Blend Improves Hair Density in Humans: Clinical Findings

Feb 9, 2026 Clinical Hair Health

Nicotinamide Riboside Blend Improves Hair Density in Humans: Clinical Findings

Objectives

To determine whether MiAc could increase mitochondrial activity and signals involved in hair growth in human cells, and whether shampoo or scalp-tonic formulations containing MiAc could improve hair density in adults with hair-loss symptoms.

Journal

International Journal of Cosmetic Science

Key Outcomes

In Vitro

In cultured human hair follicle cells and skin fibroblasts, MiAc increased cellular energy, mitochondrial content, and signals associated with hair growth. It also improved cell survival and movement.

In Vivo

Both shampoo and scalp tonic MiAc formulations produced significant improvements in hair density and growth, with no adverse effects reported during the study.

Duration

24 weeks

Dose

Dose unspecified*

*Intervention consisted of a shampoo or scalp tonic containing Mito-Activator Complex (MiAc). MIAc consisted of nicotinamide, NR, NAD+, and epigallocatechin gallate (EGCG).

Study Design

In Vitro
Laboratory experiments in human hair-follicle cells and skin fibroblasts

In Vivo
Controlled study in 52 adults with hair-loss symptoms

See Published Study

Clinical

Nicotinamide Riboside Increases NAD+ More Than NMN: Clinical Findings

Objectives To investigate the blood and brain pharmacokinetics of NR and NMN in healthy individuals and PD patients. Journal iScience Key Outcomes During the pilot portion, NR supplementation did...