Nicotinamide Riboside Reduces Liver Inflammation and DNA Damage: Preclinical Findings

Synopsis Obesity increases the risk of liver cancer (hepatocellular carcinoma, HCC), but the exact mechanisms were unclear. This study found that a liver protein called URI links excess nutrients ...

Nicotinamide Riboside Reverses Age-Related Fatty Liver Disease: Preclinical Findings

Synopsis Aging is a major risk factor for non-alcoholic fatty liver disease (NAFLD), but the biological link between the two has remained unclear. This study shows that declining levels of nicotin...

Nicotinamide Ribosides Reverses Fatty Liver Disease: Preclinical Findings

Synopsis Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease, with no approved drug treatments. This study demonstrates that a high-fat, high-sugar diet reduces ...

Increasing NAD+ with Nicotinamide Riboside Prevents Liver Cancer Driven by URI: Preclinical Findings

Synopsis The molecular causes of liver cancer (hepatocellular carcinoma, HCC) are not fully understood. This study used genetically modified mice to show that when liver cells produce too much of ...